Depressed pregnancy women who were using SSRIs or were untreated both were at risk for preterm birth, with rates exceeding 20%. Infants who were exposed to either SSRIs or depression in utero were more likely to be born preterm when compared with infants with no exposure or partial exposure to either. The use of SSRIs did not increase the risk for minor physical anomalies for infants, or reduced maternal weight gain. Infant birth weights were equivalent, and other neonatal outcomes were similar except for the 5 minute APGAR ratings.
Although we have no knowledge regarding caffeine withdrawal symptoms, apparently drinking up to three caffeinated beverages daily does not effect birthweight, prematurity, or fetal growth. Thus, a study by Jahanfar et al., showed no benefit to those women who avoid caffeine intake during early pregnancy.